3-Pyridinecarboxylicacid, 2-amino-4,6-dichloro-, methyl ester CAS 1044872-40-3

3-Pyridinecarboxylicacid, 2-amino-4,6-dichloro-, methyl ester - Names and Identifiers

Name	3-Pyridinecarboxylicacid, 2-amino-4,6-dichloro-, methyl ester
Synonyms	3-Pyri 2-amino-4,6-dichloro-, methyl ester Methyl 2-aMino-4,6-dichloronicotinate 2-Amino-4,6-dichloro-nicotinicacidmethylester 2-Amino-4,6-dichloro-nicotinic acid methyl ester Methyl 2-amino-4,6-dichloropyridine-3-carboxylate 2-Amino-4,6-dichloropyridine-3-carboxylic acid methyl ester 3-Pyridinecarboxylicacid, 2-amino-4,6-dichloro-, methyl ester 3-Pyridinecarboxylicacid, 2-amino-4,6-dichloro-, methyl este...
CAS	1044872-40-3
EINECS	1533716-785-6

3-Pyridinecarboxylicacid, 2-amino-4,6-dichloro-, methyl ester - Physico-chemical Properties

Molecular Formula	C7H6Cl2N2O2
Molar Mass	221.04
Density	1.506
Boling Point	319.135 °C at 760 mmHg
Flash Point	146.808 °C
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

3-Pyridinecarboxylicacid, 2-amino-4,6-dichloro-, methyl ester - Introduction

Methyl 2-amino -4, 6-dichloronicotinate is an organic compound whose chemical formula is C7H6Cl2NO2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 2-amino -4, 6-dichloronicotinic acid methyl ester is colorless or slightly yellow crystal.
-Solubility: It is soluble in some organic solvents such as ethanol and dichloromethane, but insoluble in water.
-Melting point: Its melting point is between 60-62°C.

Use:
-Drug intermediate: 2-amino -4, 6-dichloronicotinic acid methyl ester is an important intermediate for the synthesis of certain drugs, such as the synthesis of anti-rheumatic drugs.

Preparation Method:
- 2-amino -4, 6-dichloronicotinic acid methyl ester can be prepared by reacting 2,4-dichloronicotinic acid methyl ester with ammonia. The reaction is generally carried out under suitable reaction conditions, such as in an organic solvent, at room temperature or at low temperature.
-reaction equation: 2,4-dichloronicotinic acid methyl ester NH3 -> 2-amino -4,6-dichloronicotinic acid methyl ester HCl

Safety Information:
- 2-amino -4, 6-dichloronicotinic acid methyl ester is an organic compound that may cause irritation and damage to the human body when exposed. Therefore, it is necessary to take appropriate protective measures during use and operation, such as wearing protective gloves and glasses, and operating in a well-ventilated environment.
-When storing, it should be stored in a dry, cool place, and away from fire and oxidants.
-When disposing of waste, local environmental laws and regulations need to be observed.